 Hugh GrantPirate Captain (voice) | Pirate Captain (voice) |
 Martin FreemanPirate with a Scarf (voice) | Pirate with a Scarf (voice) |
 Imelda StauntonQueen Victoria (voice) | Queen Victoria (voice) |
 David TennantCharles Darwin (voice) | Charles Darwin (voice) |
 Jeremy PivenBlack Bellamy (voice) | Black Bellamy (voice) |
 Salma Hayek PinaultCutlass Liz (voice) | Cutlass Liz (voice) |
 Lenny HenryPeg Leg Hastings (voice) | Peg Leg Hastings (voice) |
 Brian BlessedThe Pirate King (voice) | The Pirate King (voice) |
 Russell ToveyThe Albino Pirate (voice) | The Albino Pirate (voice) |
 Brendan GleesonThe Pirate with Gout (voice) | The Pirate with Gout (voice) |
 Ashley JensenThe Surprisingly Curvaceous Pirate (voice) | The Surprisingly Curvaceous Pirate (voice) |
 Ben WhiteheadThe Pirate Who Likes Sunsets and Kittens (voice) | The Pirate Who Likes Sunsets and Kittens (voice) |
| MMike CooperAdmiral Collingwood (voice) | Admiral Collingwood (voice) |
 David SchneiderScarlett Morgan (voice) | Scarlett Morgan (voice) |
| TTom DoggartAdditional Voices (voice) | Additional Voices (voice) |
| SSophie JerroldAdditional Voices (voice) | Additional Voices (voice) |
| SSophie LaughtonAdditional Voices (voice) | Additional Voices (voice) |
 Peter LordAdditional Voices (voice) | Additional Voices (voice) |
 Kayvan NovakAdditional Voices (voice) | Additional Voices (voice) |
 David SchaalAdditional Voices (voice) | Additional Voices (voice) |
