In one of his rare movie starring assignments, William Talman (Hamilton Burger on TV's Perry Mason) plays a dual role in The Persuader. Talman is seen as gunslinger Matt Bonham and his twin brother, preacher Mark Bonham. When Mark is killed by outlaw leader Bick Justin, Matt takes his brother's place in the pulpit, ramming the Fear of God down the throats of the wanton townspeople. Impressed by Bonham's courage, the townsfolk begin to follow the straight and narrow path.
| Actor | Role |
|---|---|
 William TalmanMatt Bonham / Mark Bonham | Matt Bonham / Mark Bonham |
 James CraigBick Justin | Bick Justin |
 Kristine MillerKathryn Bonham | Kathryn Bonham |
 Darryl HickmanToby Bonham | Toby Bonham |
 Georgia LeeCora Nicklin | Cora Nicklin |
 Alvy MooreWilly Williams | Willy Williams |
 Gregory WalcottJim Cleery | Jim Cleery |
 Joyce ComptonJulie | Julie |
| PPaul EnglePaul Bonham | Paul Bonham |
| JJason JohnsonMorse Fowler | Morse Fowler |
| WWendy StuartPolly Landis | Polly Landis |