 George ClooneyCapt. Billy Tyne | Capt. Billy Tyne |
 Mark WahlbergBobby Shatford | Bobby Shatford |
 Diane LaneChristina "Chris" Cotter | Christina "Chris" Cotter |
 John C. ReillyDale "Murp" Murphy | Dale "Murp" Murphy |
 William FichtnerDavid "Sully" Sullivan | David "Sully" Sullivan |
 Mary Elizabeth MastrantonioLinda Greenlaw | Linda Greenlaw |
 John HawkesMike "Bugsy" Moran | Mike "Bugsy" Moran |
 Dash MihokSgt. Jeremy Mitchell | Sgt. Jeremy Mitchell |
 Karen AllenMelissa Brown | Melissa Brown |
 Bob GuntonAlexander McAnally III | Alexander McAnally III |
 Cherry JonesEdie Bailey | Edie Bailey |
 Allen PayneAlfred Pierre | Alfred Pierre |
 Josh HopkinsCapt. Darryl Ennis | Capt. Darryl Ennis |
 Todd KimseyLt. Rob Pettit | Lt. Rob Pettit |
 Christopher McDonaldTodd Gross | Todd Gross |
 Michael IronsideBob Brown | Bob Brown |
 Rusty SchwimmerIrene "Big Red" Johnson | Irene "Big Red" Johnson |
 Janet WrightEthel Shatford | Ethel Shatford |
 Chris PalermoFlight Engineer Borgers | Flight Engineer Borgers |
 Wiley M. PickettSgt. Millard Jones | Sgt. Millard Jones |
| HHayden TankDale Murphy, Jr. | Dale Murphy, Jr. |
 Merle KennedyDebra Murphy | Debra Murphy |
 Jennifer SommerfeldAlfred Pierre's Girlfriend | Alfred Pierre's Girlfriend |
 Joseph D. ReitmanDouglas Kosco | Douglas Kosco |
 Sandy WardQuentin - The Old Timer | Quentin - The Old Timer |
| MMelissa SamuelsPam - Todd Gross' Assistant | Pam - Todd Gross' Assistant |
 Steven BarrCommander Brudnicki | Commander Brudnicki |
 Billy MayoC-130 Pilot | C-130 Pilot |
 Marcio RosarioPool Player (uncredited) | Pool Player (uncredited) |
| BBrad MartinGloucester Fisherman #1 (uncredited) | Gloucester Fisherman #1 (uncredited) |
