American federal agent Clark Stuart is on assignment in Santa Fe to draw up a trade agreement with the newly installed Mexican governor. Meanwhile, Walter Jamison leads a wagon train from Missouri, hoping to take advantage of the new agreement. Among Jamison's passenger are famed frontiersman Jim Bowie and a very youthful Kit Carson. The destinies of all these personalities intersect when villainous ex-governor DuPrey schemes to undermine the treaty and take over the New Mexico territory for his own vile purposes. Somewhere along the way, Davy Crockett joins the "good guys" in their efforts to thwart the despicable DuPrey.
| Actor | Role |
|---|---|
 Ray CorriganClark Stuart | Clark Stuart |
 Hoot GibsonWalter Jamison | Walter Jamison |
 LeRoy MasonLt. Gov. Alfredo Dupray (as Leroy Mason) | Lt. Gov. Alfredo Dupray (as Leroy Mason) |
 Duncan RenaldoZamorro | Zamorro |
 Sammy McKimChristopher Kit Carson | Christopher Kit Carson |
 Hal TaliaferroJim Bowie | Jim Bowie |
 Jack PerrinDavy Crockett [Chs. 5-12] | Davy Crockett [Chs. 5-12] |
| EEd 'Oscar' PlattOscar (as Oscar) | Oscar (as Oscar) |
| LLou FultonElmer (as Elmer) | Elmer (as Elmer) |
 Jean CarmenThe Rider (as Julia Thayer) | The Rider (as Julia Thayer) |
 Yakima CanuttTom | Tom |
| MMaston WilliamsMacklin - Henchman (as Matson Williams) | Macklin - Henchman (as Matson Williams) |
| DDuke TaylorBill - Henchman | Bill - Henchman |
| LLoren RiebeCave Sentry / Pedro - Henchman | Cave Sentry / Pedro - Henchman |
| GGeorge DeNormandLuke Oldham [Chs. 4-5] | Luke Oldham [Chs. 4-5] |