 Liev SchreiberRobert Thorn | Robert Thorn |
 Julia StilesKatherine Thorn | Katherine Thorn |
 Mia FarrowMrs. Baylock | Mrs. Baylock |
 David ThewlisKeith Jennings | Keith Jennings |
 Pete PostlethwaiteFather Brennan | Father Brennan |
 Michael GambonBugenhagen | Bugenhagen |
 Seamus Davey-FitzpatrickDamien Thorn | Damien Thorn |
 Predrag BjelacVatican Observatory Priest | Vatican Observatory Priest |
| CCarlo SabatiniCardinal Fabretti | Cardinal Fabretti |
 Bohumil ŠvarcPope | Pope |
 Giovanni Lombardo RadiceFather Spiletto | Father Spiletto |
| BBaby ZikovaDamien - Newborn | Damien - Newborn |
| BBaby MorvasDamien - Newborn | Damien - Newborn |
| BBaby MullerDamien - Newborn | Damien - Newborn |
| BBaby LiteraDamien - Newborn | Damien - Newborn |
| TTomas WoolerDamien - 2 Years Old | Damien - 2 Years Old |
| RRafael SallasRome Embassy Marine | Rome Embassy Marine |
| MMarshall CuppAmbassador Steven Haines | Ambassador Steven Haines |
 Martin 'Mako' HindyHaines' Limo Driver | Haines' Limo Driver |
 Amy HuckNanny | Nanny |
| VVince ValituttiBirthday Party Photographer | Birthday Party Photographer |
| KKlara LowMom at Birthday Party | Mom at Birthday Party |
| LLaurie TallackTabloid Reporter #1 | Tabloid Reporter #1 |
 MyAnna BuringTabloid Reporter #2 | Tabloid Reporter #2 |
 Harvey StephensTabloid Reporter #3 | Tabloid Reporter #3 |
 Kammy DarweishSaudi Ambassador | Saudi Ambassador |
 Reggie AustinTom Portman | Tom Portman |
 Tonya GravesThorn's Secretary | Thorn's Secretary |
| CChanga BellLondon Embassy Guard | London Embassy Guard |
 Janet HenfreyMrs. Horton | Mrs. Horton |
