 Audrey HepburnSister Luke | Sister Luke |
 Peter FinchDr. Fortunati | Dr. Fortunati |
 Edith EvansRev. Mother Emmanuel | Rev. Mother Emmanuel |
 Peggy AshcroftMother Mathilde | Mother Mathilde |
 Dean JaggerDr. Hubert Van Der Mal | Dr. Hubert Van Der Mal |
 Mildred DunnockSister Margharita | Sister Margharita |
 Beatrice StraightMother Christophe | Mother Christophe |
 Patricia CollingeSister William | Sister William |
 Rosalie CrutchleySister Eleanor | Sister Eleanor |
 Ruth WhiteMother Marcella | Mother Marcella |
 Barbara O'NeilMother Didyma | Mother Didyma |
 Margaret PhillipsSister Pauline | Sister Pauline |
| PPatricia BosworthSimone | Simone |
 Colleen DewhurstDangerous Hospital Patient | Dangerous Hospital Patient |
 Stephen MurrayChaplain | Chaplain |
 Lionel JeffriesDr. Goovaerts | Dr. Goovaerts |
 Niall MacGinnisFather Vermeuhlen | Father Vermeuhlen |
 Eva KotthausSister Marie | Sister Marie |
| MMolly UrquhartSister Augustine | Sister Augustine |
 Dorothy AlisonSister Aurelie | Sister Aurelie |
 Jeanette SterkeLouise | Louise |
 Errol JohnIllunga | Illunga |
| DDiana LambertLisa | Lisa |
 Orlando MartinsKalulu | Kalulu |
 Penelope HornerJeanette Milonet (uncredited) | Jeanette Milonet (uncredited) |
| CCharles LambPascin (uncredited) | Pascin (uncredited) |
 Ave NinchiSister Bernard (uncredited) | Sister Bernard (uncredited) |
 Richard O'SullivanPierre (uncredited) | Pierre (uncredited) |
| FFrank SinguineauMurderer of Sister Aurelie (uncredited) | Murderer of Sister Aurelie (uncredited) |
 Elsa Albani(uncredited) | (uncredited) |
