Follows Helen "Nana" Lewis, a feisty chess master, and her grandsons, as they embark on a road trip to support her rise to state championships.
| Actor | Role |
|---|---|
 Mercedes RuehlNana | Nana |
 Nolan GouldAndrew | Andrew |
 Will PeltzCody | Cody |
 Tony ToddJack | Jack |
 Sierra McCormickSarah | Sarah |
 Christina MooreCindy Trublen | Cindy Trublen |
 Morgan FairchildFrancesca | Francesca |
 Beth BroderickKitty | Kitty |
 Nicky WhelanJennifer | Jennifer |
 Charlene TiltonEsther | Esther |
 Margaret AveryGladys | Gladys |
 Gina HirazumiLisa Chen | Lisa Chen |
 Aaron Quinn LongStephen Farlow | Stephen Farlow |
 Katie SarifeLinda Jenkins | Linda Jenkins |
 Jordan James SmithJoe | Joe |
 Karl LichtRick Evans | Rick Evans |
 Dixie LightCarmensita | Carmensita |
 Carlos SanzLuis Amarillo | Luis Amarillo |
| KKyle WallenPaul | Paul |
 Peter JohnsonRobert Hill | Robert Hill |
 Taso MikroulisRandall | Randall |
 Steven A. MillerNurse Elliot | Nurse Elliot |
 John NewbergAbe | Abe |
| BBruce TaylorEd | Ed |
 Nicholas David KingPreston | Preston |
| CCallaghan BelleTracy | Tracy |
 Chloe CarabasiRachel | Rachel |
 Rose BiancoHilda Suarez | Hilda Suarez |
| MMarina DeeJasmine | Jasmine |
 Mike ManningTodd Stevens | Todd Stevens |