 Jennifer LopezMother | Mother |
 Lucy PaezZoe | Zoe |
 Omari HardwickCruise | Cruise |
 Joseph FiennesAdrian | Adrian |
 Gael García BernalHector | Hector |
 Paul RaciJons | Jons |
 Jesse GarciaTarantula | Tarantula |
 Yvonne Senat JonesSonya | Sonya |
 Edie FalcoSAIC Eleanor Williams | SAIC Eleanor Williams |
 Michael Karl RichardsZoe's Adopted Dad | Zoe's Adopted Dad |
 Link BakerMarcus Stone | Marcus Stone |
 Mayumi YoshidaC-Section Nurse | C-Section Nurse |
 Ryan CowieNew Father | New Father |
 Todd MatthewsFed at Zoe's House | Fed at Zoe's House |
 Yadier FernándezCuban OB / GYN | Cuban OB / GYN |
 Olivia LucasMedical Clinic Nurse | Medical Clinic Nurse |
 Mehdi RegraguiArms Dealer | Arms Dealer |
 Jay Cardinal VilleneuveExal Room Doctor | Exal Room Doctor |
| DDaniel WhittakerFedEx Worker | FedEx Worker |
 Richard MiroFBI Tip Line (voice) | FBI Tip Line (voice) |
| JJuan José RodríguezCuban Cab Driver | Cuban Cab Driver |
| KKarl McMillanCar Rental Manager | Car Rental Manager |
 Noah CrawfordEl Globo (uncredited) | El Globo (uncredited) |
 Fahim FazliAfghan Hammam (uncredited) | Afghan Hammam (uncredited) |
 Saif MohsenMohamed (uncredited) | Mohamed (uncredited) |
 Gabriel BonillaLooper (voice / uncredited) | Looper (voice / uncredited) |
| YYorkie JoaquinCleaner (uncredited) | Cleaner (uncredited) |
| LLeslie LluvetLooper (voice / uncredited) | Looper (voice / uncredited) |
 Carlos RoblesKentucky Sniper (uncredited) | Kentucky Sniper (uncredited) |
 Isaac Gonzalez RossiLooper (voice / uncredited) | Looper (voice / uncredited) |
