Holmes finds that the disappearance of respectable middle class Neville St. Clair may be linked to a filthy beggar living above an opium den.
| Actor | Role |
|---|---|
 Eille NorwoodSherlock Holmes | Sherlock Holmes |
| HHubert WillisDr. John Watson | Dr. John Watson |
| RRobert VallisNeville St. Clair | Neville St. Clair |
| PPaulette del BazeMrs. Nellie St. Clair | Mrs. Nellie St. Clair |
| MMme. d'EsterreMrs. Hudson | Mrs. Hudson |