15th-century physician Robert Briand runs a leper colony that accepts new residents who suffer from the ravages of syphilis. When the beautiful Marie-Blanche is brought to the grim, prison-like facility, Briand finds she displays no apparent signs of disease. He risks everything when he falls in love with the woman and makes plans to run away with her.
| Actor | Role |
|---|---|
 Robin RenucciRobert Briand | Robert Briand |
 Isabelle PascoMarte-Blanche | Marte-Blanche |
 Piera Degli EspostiThérèse | Thérèse |
 Paolo RossiLaurent Vita | Laurent Vita |
 Maurizio DonadoniPhilippe | Philippe |
 Franco CittiCigal | Cigal |
 Andrzej SewerynPedlar | Pedlar |
 Gianfranco BarraSodomite | Sodomite |
| VValeria MagliOlivia | Olivia |
| SSerge SpiraFrançois, guard | François, guard |
 Erland JosephsonRobert's Father | Robert's Father |
 Carole BouquetEleonore | Eleonore |