Miles Machree (J. Warren Kerrigan) meets Irish-American Sheila Lynch (Fritzi Brunette) when she travels through Ireland with her father (James O. Barrows). Soon after the Lynch's return to the States, Miles follows, and through his uncle's connections, gets a job on the New York City police force.
| Actor | Role |
|---|---|
 J. Warren KerriganMiles Machree | Miles Machree |
 Aggie HerringMother Machree | Mother Machree |
 James O. BarrowsTimothy Lynch | Timothy Lynch |
 Fritzi BrunetteSheila Lynch | Sheila Lynch |
 Wedgwood NowellAllyn Dexter | Allyn Dexter |
 Joseph J. DowlingDr. Leon Wilson / Hugo Strauss | Dr. Leon Wilson / Hugo Strauss |
| WWilliam EllingfordMalachi Nolan | Malachi Nolan |