 Chris PrattEmmet Brickowski / Rex Dangervest (voice) | Emmet Brickowski / Rex Dangervest (voice) |
 Elizabeth BanksWyldstyle / Lucy (voice) | Wyldstyle / Lucy (voice) |
 Will ArnettBatman (voice) | Batman (voice) |
 Tiffany HaddishQueen Watevra Wa'Nabi (voice) | Queen Watevra Wa'Nabi (voice) |
 Stephanie BeatrizGeneral Mayhem / Sweet Mayhem (voice) | General Mayhem / Sweet Mayhem (voice) |
 Alison BrieUnikitty / Ultrakatty (voice) | Unikitty / Ultrakatty (voice) |
 Nick OffermanMetalBeard (voice) | MetalBeard (voice) |
 Charlie DayBenny (voice) | Benny (voice) |
 Maya RudolphMom | Mom |
 Will FerrellPresident Business / Dad | President Business / Dad |
 Jadon SandFinn | Finn |
 Brooklynn PrinceBianca | Bianca |
 Channing TatumSuperman (voice) | Superman (voice) |
 Jonah HillGreen Lantern (voice) | Green Lantern (voice) |
 Richard AyoadeIce Cream Cone (voice) | Ice Cream Cone (voice) |
 Ben SchwartzBanarnar (voice) | Banarnar (voice) |
 Noel FieldingBalthazar (voice) | Balthazar (voice) |
 Jason MomoaAquaman (voice) | Aquaman (voice) |
 Cobie SmuldersWonder Woman (voice) | Wonder Woman (voice) |
 Ike BarinholtzLex Luthor (voice) | Lex Luthor (voice) |
 Ralph FiennesAlfred Pennyworth (voice) | Alfred Pennyworth (voice) |
 Will ForteAbraham Lincoln (voice) | Abraham Lincoln (voice) |
 Jimmy O. YangEnthusiastic Zebra (voice) | Enthusiastic Zebra (voice) |
 Jorma TacconeLarry Poppins (voice) | Larry Poppins (voice) |
 Bruce WillisBruce Willis (voice) | Bruce Willis (voice) |
 Gary PaytonGary Payton (voice) | Gary Payton (voice) |
 Sheryl SwoopesSheryl Swoopes (voice) | Sheryl Swoopes (voice) |
| TTodd HansenGandalf / Swamp Creature (voice) | Gandalf / Swamp Creature (voice) |
| DDoug NicholasSurfer Dave / Chainsaw Dave / Purgatory Dave (voice) | Surfer Dave / Chainsaw Dave / Purgatory Dave (voice) |
| LLiam KnightDuplo / Heart / Star / Sewer Babies (voice) | Duplo / Heart / Star / Sewer Babies (voice) |
