 William PowellPhilo Vance | Philo Vance |
 Mary AstorHilda Lake | Hilda Lake |
 Eugene PalletteDetective Heath | Detective Heath |
 Ralph MorganRaymond Wrede | Raymond Wrede |
 Robert McWadeDistrict Attorney Markham | District Attorney Markham |
 Robert BarratArcher Coe | Archer Coe |
 Frank ConroyBrisbane Coe | Brisbane Coe |
 Etienne GirardotDr. Doremus | Dr. Doremus |
| JJames LeeLiang | Liang |
 Paul CavanaghThomas MacDonald | Thomas MacDonald |
 Arthur HohlGamble the Butler | Gamble the Butler |
 Helen VinsonDoris Delafield | Doris Delafield |
 Jack La RueEduardo Grassi | Eduardo Grassi |
 Harry AllenSandy (uncredited) | Sandy (uncredited) |
 Wade BotelerDesk Sergeant Mellish (uncredited) | Desk Sergeant Mellish (uncredited) |
 Don BrodiePolice Photographer (uncredited) | Police Photographer (uncredited) |
 James BurkePoliceman Who Lets Dog Out (uncredited) | Policeman Who Lets Dog Out (uncredited) |
 George ChandlerReporter at Police Station (uncredited) | Reporter at Police Station (uncredited) |
 Spencer ChartersSergeant Snitkin (uncredited) | Sergeant Snitkin (uncredited) |
 Virginia DabneyGirl (uncredited) | Girl (uncredited) |
 Milton KibbeeReporter (uncredited) | Reporter (uncredited) |
 Henry O'NeillDubois (uncredited) | Dubois (uncredited) |
 Paul PanzerBaggage Clerk (uncredited) | Baggage Clerk (uncredited) |
| CCliff SaumPoliceman on Night Patrol (uncredited) | Policeman on Night Patrol (uncredited) |
| SSkippyTerrier at Dog Show (uncredited) | Terrier at Dog Show (uncredited) |
| AArthur ThalassoDetective (uncredited) | Detective (uncredited) |
| MMonte VandergriftDetective (uncredited) | Detective (uncredited) |
 Leo WhiteChicago Hotel Clerk (uncredited) | Chicago Hotel Clerk (uncredited) |
 Renee WhitneyTelephone Operator (uncredited) | Telephone Operator (uncredited) |
 Charles Cahill WilsonDetective Hennessy (uncredited) | Detective Hennessy (uncredited) |
