 Mel BlancBarney Rubble / Dino / Mr. Spacely (voice) | Barney Rubble / Dino / Mr. Spacely (voice) |
 Daws ButlerElroy Jetson / W.C. Cogswell / Henry Orbit (voice) | Elroy Jetson / W.C. Cogswell / Henry Orbit (voice) |
 Don MessickAstro / R.U.D.I / Mac / Announcer / Store Manager / Robot (voice) | Astro / R.U.D.I / Mac / Announcer / Store Manager / Robot (voice) |
 Henry CordenFred Flintstone / Knight (voice) | Fred Flintstone / Knight (voice) |
| JJon BaumanIggy (voice) | Iggy (voice) |
 Hamilton CampTurk Tarpit (voice) | Turk Tarpit (voice) |
 Julie McWhirterBetty Rubble / Jet Rivers / Investor / Panelist / Harem Girl (as Julie Dees) (voice) | Betty Rubble / Jet Rivers / Investor / Panelist / Harem Girl (as Julie Dees) (voice) |
 George O'HanlonGeorge Jetson (voice) | George Jetson (voice) |
 Penny SingletonJane Jetson (voice) | Jane Jetson (voice) |
 John StephensonMr. Slate / Moderator / Investor / Poker Player (voice) | Mr. Slate / Moderator / Investor / Poker Player (voice) |
 Brenda VaccaroDidi (voice) | Didi (voice) |
 Jean Vander PylWilma Flintstone / Rosie / Mrs. Spacely (voice) | Wilma Flintstone / Rosie / Mrs. Spacely (voice) |
 Janet WaldoJudy Jetson / Female Computer (voice) | Judy Jetson / Female Computer (voice) |
 Frank WelkerDan Rathmoon / Johnny / Mr. Goldbrick (voice) | Dan Rathmoon / Johnny / Mr. Goldbrick (voice) |
| PPatric Zimmerman(voice) | (voice) |
