This 12-part serial concerns the efforts of the infamous James brothers (of which Jesse was a prominent member) to become normal everyday citizens. Of course, there's no room in the Wild West for reformed outlaws, and the duo inevitably find themselves caught up in showdowns and robberies.
| Actor | Role |
|---|---|
 Keith RichardsJesse James | Jesse James |
 Robert BiceFrank James | Frank James |
 Noel NeillPeg Royer | Peg Royer |
 Roy BarcroftAce Marlin | Ace Marlin |
 Patricia KnoxBelle Calhoun | Belle Calhoun |
 Lane BradfordMonk Tucker | Monk Tucker |
 Gene RothMarshal Rand [Chs. 10-12] | Marshal Rand [Chs. 10-12] |
 John HamiltonLon Royer [Ch.1] | Lon Royer [Ch.1] |
 Edmund CobbThe Sheriff [Chs. 6-8] | The Sheriff [Chs. 6-8] |
 Hank PattersonDuffy [Ch. 4] / Duffy [11] | Duffy [Ch. 4] / Duffy [11] |
 Dale Van SickelHarry Sharkey / Henry Simpson (Chapters 3-4) | Harry Sharkey / Henry Simpson (Chapters 3-4) |
| TTom SteeleSlim, Lanky Royer Employee [Ch.1] / Drake, Lanky Henchman Guarding Simpson [Ch.4] / Henchman Guarding Wagon [Ch.11] | Slim, Lanky Royer Employee [Ch.1] / Drake, Lanky Henchman Guarding Simpson [Ch.4] / Henchman Guarding Wagon [Ch.11] |
 Lee Roberts'Brandy' Jones [Chs. 6-7] | 'Brandy' Jones [Chs. 6-7] |
 Frank O'ConnorRimrock Citizen | Rimrock Citizen |
 Marshall ReedDutch | Dutch |
 Chuck RobersonTownsman (uncredited) | Townsman (uncredited) |