 Jennifer AnistonAnnie Hughes (voice) | Annie Hughes (voice) |
 Harry Connick Jr.Dean McCoppin (voice) | Dean McCoppin (voice) |
 Vin DieselThe Iron Giant (voice) | The Iron Giant (voice) |
 James GammonForeman Marv Loach / Floyd Turbeaux (voice) | Foreman Marv Loach / Floyd Turbeaux (voice) |
 Cloris LeachmanMrs. Lynley Tensedge (voice) | Mrs. Lynley Tensedge (voice) |
 Christopher McDonaldKent Mansley (voice) | Kent Mansley (voice) |
 John MahoneyGeneral Rogard (voice) | General Rogard (voice) |
 Eli MarienthalHogarth Hughes (voice) | Hogarth Hughes (voice) |
 M. Emmet WalshEarl Stutz (voice) | Earl Stutz (voice) |
 Jack AngelAdditional Voices (voice) | Additional Voices (voice) |
 Bob BergenAdditional Voices (voice) | Additional Voices (voice) |
 Mary Kay BergmanAdditional Voices (voice) | Additional Voices (voice) |
 Michael BirdAdditional Voices (voice) | Additional Voices (voice) |
| DDevon Cole BorisoffAdditional Voices (voice) | Additional Voices (voice) |
 Rodger BumpassAdditional Voices (voice) | Additional Voices (voice) |
 Robert ClotworthyAdditional Voices (voice) | Additional Voices (voice) |
 Jennifer DarlingAdditional Voices (voice) | Additional Voices (voice) |
| ZZack EgintonAdditional Voices (voice) | Additional Voices (voice) |
 Paul EidingAdditional Voices (voice) | Additional Voices (voice) |
 Bill FarmerAdditional Voices (voice) | Additional Voices (voice) |
 Charles HowertonAdditional Voices (voice) | Additional Voices (voice) |
 Ollie JohnstonAdditional Voices (voice) | Additional Voices (voice) |
 Sherry LynnAdditional Voices (voice) | Additional Voices (voice) |
 Mickie McGowanAdditional Voices (voice) | Additional Voices (voice) |
| RRyan O'DonohueAdditional Voices (voice) | Additional Voices (voice) |
 Phil ProctorAdditional Voices (voice) | Additional Voices (voice) |
 Frank ThomasAdditional Voices (voice) | Additional Voices (voice) |
 Patti TippoAdditional Voices (voice) | Additional Voices (voice) |
 Brian TochiAdditional Voices (voice) | Additional Voices (voice) |
| CCarole JeghersFirefighter Woman (voice) (uncredited) | Firefighter Woman (voice) (uncredited) |
