Cardiac surgeon Alex Marsden has an affair with Marcella Duggan, but then finds himself having to operate on her husband Larry, who is also his friend.
| Actor | Role |
|---|---|
 Nigel HaversDr. Alex Marsden | Dr. Alex Marsden |
 Orla BradyMarcella Duggan | Marcella Duggan |
 Lorcan CranitchLarry Duggan | Larry Duggan |
 John CastleCharlie Hawkesmore | Charlie Hawkesmore |
 Claire YarlettSarah | Sarah |
 Michael TroughtonBill Lester | Bill Lester |
| SSam DastorV. J. Krishna | V. J. Krishna |
 Alexandra GilbreathRachel Ryan | Rachel Ryan |
| DDavid AshtonPhil Mycroft | Phil Mycroft |
| TToby SalamanCoronor | Coronor |
| GGillian HannaMargot | Margot |
 Gabrielle GlaisterPaula Shears | Paula Shears |
 Roger MorlidgeMaggot | Maggot |
| SSylvester SalmonJoshua Unussu | Joshua Unussu |
| PPauline MonroHilda | Hilda |
 Nicholas HutchisonProfusionist | Profusionist |
| JJoy HarrisonAnaesthetist | Anaesthetist |
 Mark AddyPhil Mycroft | Phil Mycroft |
| PPoppy SmithWard Nurse | Ward Nurse |
| DDennis BanksTheatre Porter | Theatre Porter |
 James BarriscaleScrub Nurse | Scrub Nurse |
| AAndrew HallettRunner | Runner |
 Adrian BowerICU Nurse | ICU Nurse |
 Margaret JohnMrs. Hughes | Mrs. Hughes |
 Kate AldertonTV Reporter | TV Reporter |
 Mark ChapmanJournalist | Journalist |