"The Hardest Button to Button" is the third White Stripes video directed by Michel Gondry, after "Fell in Love with a Girl" and "Dead Leaves and the Dirty Ground" (two years later, he would direct the music video for "The Denial Twist").
| Actor | Role |
|---|---|
 Jack WhiteSelf | Self |
 Meg WhiteSelf | Self |
 BeckMan in White Suit | Man in White Suit |