During the American Civil War (1861-1865), farmers Jesse and Frank James decided to form an armed gang to face the Union troops using guerrilla warfare.
| Actor | Role |
|---|---|
 Wendell CoreyFrank James | Frank James |
 Macdonald CareyJesse James | Jesse James |
 Ellen DrewBee Moore | Bee Moore |
 Ward BondMaj. Marshal Trowbridge | Maj. Marshal Trowbridge |
 Bruce BennettCole Younger | Cole Younger |
 Anne RevereMrs. Samuels | Mrs. Samuels |
 Edgar BuchananDr. Samuels | Dr. Samuels |
 Bill WilliamsJim Younger | Jim Younger |
| AAlan WellsDick Liddil | Dick Liddil |