Poof comes into existence when Cosmo and Wanda decide to have a child of their own, and Timmy wishes it so. However, because the fairy baby's magic is developing and uncontrollable, villains called the anti-fairies (polar opposite of fairies) and pixies (business fairies) seek to steal the fairy baby so they can take over the fairies' home, Fairy World.
| Actor | Role |
|---|---|
 Tara StrongTimmy Turner / Poof (voice) | Timmy Turner / Poof (voice) |
 Daran NorrisCosmo / Dad (voice) | Cosmo / Dad (voice) |
 Susanne BlakesleeWanda / Mom | Wanda / Mom |
 Jane CarrMama Cosma (voice) | Mama Cosma (voice) |
 Mary HartFairy Hart (voice) | Fairy Hart (voice) |
 Butch HartmanDr. Rip Studwell (voice) | Dr. Rip Studwell (voice) |
 Tom KennyCupid / Fairy Soldier (voice) | Cupid / Fairy Soldier (voice) |
 Ben SteinHead Pixie / Sanderson (voice) | Head Pixie / Sanderson (voice) |
 Jim WardChet Ubetcha (voice) | Chet Ubetcha (voice) |