 David SpadeKuzco (voice) | Kuzco (voice) |
 John GoodmanPacha (voice) | Pacha (voice) |
 Eartha KittYzma (voice) | Yzma (voice) |
 Patrick WarburtonKronk (voice) | Kronk (voice) |
 Wendie MalickChicha (voice) | Chicha (voice) |
 Kellyann KelsoChaca (voice) | Chaca (voice) |
 Eli Russell LinnetzTipo (voice) | Tipo (voice) |
 Stephen J. AndersonAdditional Voices (voice) | Additional Voices (voice) |
 Bob BergenBucky / Additional Voices (voice) | Bucky / Additional Voices (voice) |
 Rodger BumpassAdditional Voices (voice) | Additional Voices (voice) |
 Robert ClotworthyAdditional Voices (voice) | Additional Voices (voice) |
 Jennifer DarlingAdditional Voices (voice) | Additional Voices (voice) |
 Patti DeutschWaitress / Additional Voices (voice) | Waitress / Additional Voices (voice) |
 John FiedlerOld Man / Additional Voices (voice) | Old Man / Additional Voices (voice) |
 Miriam FlynnAdditional Voices (voice) | Additional Voices (voice) |
| GGeri Lee GorowskiAdditional Voices (voice) | Additional Voices (voice) |
 Sherry LynnAdditional Voices (voice) | Additional Voices (voice) |
 Danny MannAdditional Voices (voice) | Additional Voices (voice) |
 Mickie McGowanAdditional Voices (voice) | Additional Voices (voice) |
| DD.F. ReynoldsAdditional Voices (voice) | Additional Voices (voice) |
 Andre StojkaAdditional Voices (voice) | Additional Voices (voice) |
 Steve SusskindAdditional Voices (voice) | Additional Voices (voice) |
 Joe WhyteOfficial / Additional Voices (voice) | Official / Additional Voices (voice) |
 Jack AngelVillagers (voice) (uncredited) | Villagers (voice) (uncredited) |
 Mark DindalKitty Yzma (voice) (uncredited) | Kitty Yzma (voice) (uncredited) |
 Bill FarmerVillagers (voice) (uncredited) | Villagers (voice) (uncredited) |
| CCarole JeghersJaguars (voice) (uncredited) | Jaguars (voice) (uncredited) |
| TTom JonesTheme Song Guy (voice) | Theme Song Guy (voice) |
 Patrick PinneyVillagers (voice) (uncredited) | Villagers (voice) (uncredited) |
 Jess HarnellAdditional Voices (voice) | Additional Voices (voice) |
