In the near future, due to a breakthrough scientific discovery by Dr. Thomas Harbor, there is now definitive proof of an afterlife. While countless people have chosen suicide to reset their existence, others try to decide what it all means. Among them is Dr. Harbor's son Will, who has arrived at his father's isolated compound with a mysterious young woman named Isla. There, they discover the strange acolytes who help Dr. Harbor with his experiments.
| Actor | Role |
|---|---|
 Jason SegelWill Harbor | Will Harbor |
 Rooney MaraIsla | Isla |
 Robert RedfordDr. Thomas Harbor | Dr. Thomas Harbor |
 Jesse PlemonsToby Harbor | Toby Harbor |
 Riley KeoughLacey | Lacey |
 Ron CanadaCooper | Cooper |
 Brian McCarthyAndy | Andy |
 Kimleigh SmithPam | Pam |
 M.J. KarmiJanice Phillips | Janice Phillips |
 Adam KhaykinOliver | Oliver |
 Mary SteenburgenInterviewer | Interviewer |
 Connor RatliffCoroner | Coroner |
 Willie C. CarpenterHospital Janitor | Hospital Janitor |
 Wendy MakkenaMom | Mom |
 Lindsay SchneblyNewscaster | Newscaster |
| RRichard O'RourkeMarvin (uncredited) | Marvin (uncredited) |
 Paul BellefeuillePat Phillips (uncredited) | Pat Phillips (uncredited) |