With guidance from their mother, five siblings overcome humble beginnings to form the renowned gospel group the Clark Sisters.
| Actor | Role |
|---|---|
 Aunjanue Ellis-TaylorMattie Moss Clark | Mattie Moss Clark |
 Raven GoodwinDenise Clark Bradford | Denise Clark Bradford |
 Kierra 'Kiki' SheardKaren Clark-Sheard | Karen Clark-Sheard |
 Christina BellTwinkie Clark-Terrell | Twinkie Clark-Terrell |
 Shelea FrazierDorinda Clark-Cole | Dorinda Clark-Cole |
 Michael XavierJ. Drew Sheard | J. Drew Sheard |
 Demore BarnesElbert Clark | Elbert Clark |
 Romaine WaiteGreg Cole | Greg Cole |
 Brandon McKnightGlynn | Glynn |
 Saad SiddiquiReza | Reza |
 Ronnie RoweJohn | John |