Tom and Jay are best friends. Tom is married to Sally and Jay is single. Tom and Jay are also stand-up comedians and their mishaps as they seek stardom as headliners are related.
| Actor | Role |
|---|---|
 Tom PatchettTom Van Brocklin | Tom Van Brocklin |
| JJay TarsesJay Luckman | Jay Luckman |
 Gwynne GilfordSally Van Brocklin | Sally Van Brocklin |
 Philip BrunsMr. Ruth | Mr. Ruth |
 Robert EmhardtDuffy | Duffy |
 Michael PatakiKelso | Kelso |
 Donna PonterottoMichelle Rosen | Michelle Rosen |
 Philip RothNathan Railoff | Nathan Railoff |
 Rick PodellImpressionist | Impressionist |
| MMadeleine FisherReceptionist | Receptionist |