A father finds himself taking care of a family that, in addition to his son and three daughters, also consists of two sons-in-law and his youngest daughter's Chinese boyfriend.
| Actor | Role |
|---|---|
 Fred MacMurrayNed Chadwick | Ned Chadwick |
 Kathleen MaguireValerie Chadwick | Valerie Chadwick |
 Darleen CarrJoan Chadwick | Joan Chadwick |
| JJane ActmanLisa Chadwick | Lisa Chadwick |
 Stephen NathanTim Chadwick | Tim Chadwick |
 Lara ParkerEileen Chadwick | Eileen Chadwick |
 Alan FudgeAlex Hawthorne | Alex Hawthorne |
 Frank Michael LiuLee Wu-Tsaung | Lee Wu-Tsaung |
 John LarchFargo | Fargo |
 Barry BostwickDuffy McTaggert | Duffy McTaggert |
 Margaret LindsayElly | Elly |
 Walter BrookeDr. Simon | Dr. Simon |
| PPat LiMadame Wu-Tsaung | Madame Wu-Tsaung |
| JJudson MorganGarvey | Garvey |
 Bruce BoxleitnerDanny | Danny |
| EElliott MontgomeryMr. Villars | Mr. Villars |
| KKim DursoSari Hawthorne | Sari Hawthorne |
| EEben GeorgeJimmy Hawthorne | Jimmy Hawthorne |
 Carlena GowerCindy Hawthorne | Cindy Hawthorne |
| RRay BallardTaxi Driver | Taxi Driver |
 Sharon CintronNurse | Nurse |
| CCarle BensenDr. Eisenberg | Dr. Eisenberg |
| MMorton LewisHerbie | Herbie |