 Jennifer LopezCatherine Deane | Catherine Deane |
 Vince VaughnPeter Novak | Peter Novak |
 Vincent D'OnofrioCarl Rudolph Stargher | Carl Rudolph Stargher |
 Catherine SutherlandAnne Marie Vicksey | Anne Marie Vicksey |
 James GammonTeddy Lee | Teddy Lee |
 Colton JamesEdward Baines | Edward Baines |
 Dylan BakerHenry West | Henry West |
 Marianne Jean-BaptisteDr. Miriam Kent | Dr. Miriam Kent |
 Gerry BeckerDr. Barry Cooperman | Dr. Barry Cooperman |
 Musetta VanderElla Baines | Ella Baines |
 Patrick BauchauLucien Baines | Lucien Baines |
 Jake WeberGordon Ramsey | Gordon Ramsey |
 Dean NorrisCole | Cole |
 Tara SubkoffJulia Hickson | Julia Hickson |
 Lauri JohnsonMrs. Hickson | Mrs. Hickson |
 John CothranAgent Stockwell | Agent Stockwell |
 Jack ConleyAgent Brock | Agent Brock |
 Kamar de los ReyesOfficer Alexander | Officer Alexander |
 Pruitt Taylor VinceDr. Reid | Dr. Reid |
 Peter SarsgaardJulia Hickson's Fiancee (uncredited) | Julia Hickson's Fiancee (uncredited) |
| CChristopher JanneySwat Team Member | Swat Team Member |
| NNicholas CasconeFBI Technician | FBI Technician |
| JJoe La PianaFBI K-9 Agent | FBI K-9 Agent |
 Jake ThomasYoung Carl Stargher | Young Carl Stargher |
| KKim Chizevsky-NichollsStargher's Victim | Stargher's Victim |
| JJennifer DayStargher's Victim | Stargher's Victim |
 Alanna VicenteStargher's Victim | Stargher's Victim |
| AAja EcholsStargher's Victim | Stargher's Victim |
 Vanessa BranchStargher's Victim | Stargher's Victim |
| EElena MaddaloStargher's Victim | Stargher's Victim |
