 Jane WymanLouise Mason | Louise Mason |
 Charles LaughtonFred K. Begley | Fred K. Begley |
 Joan BlondellAnnie Rawlins | Annie Rawlins |
 Richard CarlsonGerald Kean | Gerald Kean |
 Agnes MooreheadMrs. Palfrey | Mrs. Palfrey |
 Don TaylorDr. Robert Palfrey | Dr. Robert Palfrey |
 Audrey TotterHelen Williams | Helen Williams |
 Cyril CusackFrank Hutchins | Frank Hutchins |
 Everett SloaneDistrict Attorney | District Attorney |
 Natalie WoodStephanie Rawlins | Stephanie Rawlins |
 Vivian VanceAlicia | Alicia |
 Carleton G. YoungHenry Palfrey | Henry Palfrey |
 Alan NapierProfessor George Carter | Professor George Carter |
 Warner AndersonBill Parker | Bill Parker |
 Les TremayneJoplin | Joplin |
| DDan SeymourPelt | Pelt |
 Dan O'HerlihyHugh Williams | Hugh Williams |
 Harry MorganCharles Hall | Charles Hall |
| GGary JacksonRobert Palfrey as a Boy | Robert Palfrey as a Boy |
| GGregory MarshallHarrison Palfrey | Harrison Palfrey |
 Dee PollockTony | Tony |
 Lillian AlbertsonMrs. Lipscott (Uncredited) | Mrs. Lipscott (Uncredited) |
 James AndersonJim Tappan (Uncredited) | Jim Tappan (Uncredited) |
| CCharles AnthonyBaby Fred Begley Jr. | Baby Fred Begley Jr. |
| GGenevieve BellHead Nurse (Uncredited) | Head Nurse (Uncredited) |
 Jack ChefeCousin (Uncredited) | Cousin (Uncredited) |
| AAllison DaniellSue (Uncredited) | Sue (Uncredited) |
 Frank GerstleDoctor (Uncredited) | Doctor (Uncredited) |
| JJo GilbertMrs. Dunlop (Uncredited) | Mrs. Dunlop (Uncredited) |
 Lisa GolmElsa (Uncredited) | Elsa (Uncredited) |
