 John WayneBreck Coleman | Breck Coleman |
 Marguerite ChurchillRuth Cameron | Ruth Cameron |
 El BrendelGus | Gus |
 Tully MarshallZeke | Zeke |
 Tyrone Power Sr.Red Flack | Red Flack |
 David RollinsDave Cameron | Dave Cameron |
| FFrederick BurtonPa Bascom | Pa Bascom |
 Ian KeithBill Thorpe | Bill Thorpe |
 Charles StevensLópez | López |
 Louise CarverGus' Mother-in-law | Gus' Mother-in-law |
 Victor AdamsonWagon Train Man (uncredited) | Wagon Train Man (uncredited) |
| PPhyllis BainbridgePioneer (uncredited) | Pioneer (uncredited) |
 Chief John Big TreeIndian (uncredited) | Indian (uncredited) |
 Ward BondSid Bascom (uncredited) | Sid Bascom (uncredited) |
 Nora BushPioneer (uncredited) | Pioneer (uncredited) |
 Martin CichyPioneer (uncredited) | Pioneer (uncredited) |
| DDon ColemanWrangler (uncredited) | Wrangler (uncredited) |
| NNancy CrowleyPioneer Child (uncredited) | Pioneer Child (uncredited) |
| CCurley DresdenPioneer (uncredited) | Pioneer (uncredited) |
| AAdabelle DriverPioneer (uncredited) | Pioneer (uncredited) |
| EEmslie EmersonSairey (uncredited) | Sairey (uncredited) |
 Alphonse EthierMarshal (uncredited) | Marshal (uncredited) |
| TTheresa GaronPioneer (uncredited) | Pioneer (uncredited) |
| WWilliam GillisPioneer (uncredited) | Pioneer (uncredited) |
 Dannie Mac GrantPioneer Boy (uncredited) | Pioneer Boy (uncredited) |
| VVirginia GriffithPioneer (uncredited) | Pioneer (uncredited) |
 Marcia HarrisMrs. Riggs (uncredited) | Mrs. Riggs (uncredited) |
 Marilyn HarrisPioneer Girl (uncredited) | Pioneer Girl (uncredited) |
| AAl HaskellPioneer (uncredited) | Pioneer (uncredited) |
 DeWitt JenningsBoat Captain Hollister (uncredited) | Boat Captain Hollister (uncredited) |
