Two tough Kentucky mountaineers join a trading expedition from St. Louis up the Missouri River to trade whisky for furs with the Blackfoot Indians. They soon discover that there is much more than the elements to contend with.
| Actor | Role |
|---|---|
 Kirk DouglasJim Deakins | Jim Deakins |
 Dewey MartinBoone Caudill | Boone Caudill |
 Elizabeth ThreattTeal Eye | Teal Eye |
 Arthur HunnicuttZeb Calloway | Zeb Calloway |
 Buddy BaerRomaine | Romaine |
 Steven Geray"Frenchy" Jourdonnais | "Frenchy" Jourdonnais |
 Henri LetondalLa Badie | La Badie |
 Hank WordenPoordevil | Poordevil |
 Jim DavisStreak | Streak |
| TThol SimonsonBoatman | Boatman |
| WWilliam SelfBoatman | Boatman |
| BBeulah ArchulettaBlackfoot Dancer | Blackfoot Dancer |
 Frank De KovaMoleface (uncredited) | Moleface (uncredited) |
 John GeorgePasserby (uncredited) | Passerby (uncredited) |
 Fred GrahamSam Eggelston (uncredited) | Sam Eggelston (uncredited) |
 Jay NovelloTrapper (uncredited) | Trapper (uncredited) |