Claire Smythson, wife of the renowned abstract artist Richard Smythson, is plunged into a late-life crisis when her husband is diagnosed with Alzheimer's disease and is in danger of not completing the paintings for his final show.
| Actor | Role |
|---|---|
 Lena OlinClaire Smythson | Claire Smythson |
 Bruce DernRichard Smythson | Richard Smythson |
 Juliet RylanceAngela Smythson | Angela Smythson |
 Avan JogiaDanny | Danny |
 Stefanie PowersAda Risi | Ada Risi |
 Tonya PinkinsLiza Caldwell | Liza Caldwell |
 Catherine CurtinJoyce | Joyce |
 Lukas HasselPhotographer | Photographer |
 Caryn WestDr. Sheila Abrams | Dr. Sheila Abrams |
 Ravi Cabot-ConyersGogo | Gogo |
| EElise SantoraJoan | Joan |
 Clare Louise FrostArtist's Model | Artist's Model |
| MMeadow NguyMelanie | Melanie |
 Josh MoweryMuseum Director | Museum Director |
 Gabriel MillmanGrocery Clerk | Grocery Clerk |
| LLaura ChaneskiJordana | Jordana |
| PPeter AlbrinkZack | Zack |
 Alexandre BagotMikey | Mikey |
 Gerardo RodriguezDoorman | Doorman |
 Dan TrumanBritish Interviewer | British Interviewer |
| PPeter SweetGallery Pedestrian | Gallery Pedestrian |
| JJake NamaroffBanquet Attendee | Banquet Attendee |
| JJerry LamonicaGallery Attendee | Gallery Attendee |
 Steve GarfantiBanquet Attendee | Banquet Attendee |
| MMonica Rani SharmaBanquet Attendee | Banquet Attendee |
 Lyssa MandelPharmacist | Pharmacist |