Grace tries to be the perfect mother and TV producer but finds trouble in juggling both.
| Actor | Role |
|---|---|
 Rosie PerezGrace Santos | Grace Santos |
 Marianne Jean-BaptisteMadeline Labelle | Madeline Labelle |
 Patti LuPoneJoan Marshall | Joan Marshall |
 Melissa LeoDr. Suzanne Pincus | Dr. Suzanne Pincus |
 Wendell PierceRoy Labelle | Roy Labelle |
 Karen DuffyMargo Lynn | Margo Lynn |
 Diego SerranoEddie Diaz | Eddie Diaz |
 Aida TurturroBrenda | Brenda |
 Rosanna DeSotoLinda | Linda |
 Michael CumpstySuzanne Pincus' Publicist | Suzanne Pincus' Publicist |
| AAlicia Renee WashingtonPatty | Patty |
 RenoCrystal | Crystal |
 Beth LittlefordLynn Shapiro | Lynn Shapiro |
 Jerry SpringerJerry Springer | Jerry Springer |
 Chris CooperRon Hacksby | Ron Hacksby |
 Elizabeth BraccoNurse | Nurse |
 Drena De NiroLori | Lori |