A romantic comedy that brings together three disparate characters who are learning to face a challenging and often confusing world as they struggle together against a common demon—sex addiction.
| Actor | Role |
|---|---|
 Mark RuffaloAdam | Adam |
 Gwyneth PaltrowPhoebe | Phoebe |
 Tim RobbinsMike | Mike |
 Josh GadNeil | Neil |
 P!nkDede | Dede |
 Patrick FugitDanny | Danny |
 Joely RichardsonKatie | Katie |
 Carol KaneRoberta | Roberta |
 Emily MeadeBecky | Becky |
 Isiah Whitlock Jr.Charles | Charles |
 Poorna JagannathanLili Kazhani | Lili Kazhani |
| TTony JoeMail executive | Mail executive |
 Jordan DeanJordan | Jordan |
 Michaela WatkinsMargo | Margo |
 Okieriete OnaodowanLou | Lou |
| NNatalia VolkodaevaAna | Ana |
 Paul UrcioliOwner | Owner |
 Kenneth MaharajCabbie | Cabbie |
 Meng AiMini-Mart Cashier | Mini-Mart Cashier |
| JJuan LeonCashier | Cashier |
| GGeoffrey MolloyMustache Man | Mustache Man |
 Maureen SebastianSubway Woman | Subway Woman |
 Marcus NevillePeter | Peter |
 Sarah BaskinWaitress | Waitress |
 Alexis SuarezParamedic | Paramedic |
 Terry WaltersFemale Addict | Female Addict |
| GGeorge DemasAddict | Addict |
 David WainAddict | Addict |
 Brian KoppelmanAddidct | Addidct |
 Geoffrey CantorAddict | Addict |