 Brian TochiLeonardo (voice) | Leonardo (voice) |
 Josh PaisRaphael (voice) / Passenger In Cab | Raphael (voice) / Passenger In Cab |
 Corey FeldmanDonatello (voice) | Donatello (voice) |
 Robbie RistMichelangelo (voice) | Michelangelo (voice) |
 Judith HoagApril O'Neil | April O'Neil |
 Elias KoteasCasey Jones | Casey Jones |
 Kevin ClashSplinter (voice) | Splinter (voice) |
 David McCharenThe Shredder / Oroku Saki (voice) | The Shredder / Oroku Saki (voice) |
 David FormanLeonardo / Gang Member | Leonardo / Gang Member |
 Martin P. RobinsonLeonardo | Leonardo |
| DDavid GreenawayRaphael | Raphael |
 Kenn ScottRaphael | Raphael |
 Leif TildenDonatello / Foot Messenger | Donatello / Foot Messenger |
 David RudmanDonatello | Donatello |
 Ernie Reyes Jr.Donatello | Donatello |
| RReggie BarnesDonatello | Donatello |
| MMichelan SistiMichaelangelo / Pizza Man | Michaelangelo / Pizza Man |
 Rickey BoydSplinter | Splinter |
| RRobert TygnerSplinter | Splinter |
 James SaitoThe Shredder / Oroko Saki | The Shredder / Oroko Saki |
 Toshishiro ObataTatsu | Tatsu |
 Michael McConnohieTatsu (voice) | Tatsu (voice) |
| MMichael TurneyDanny Pennington | Danny Pennington |
 Jay PattersonCharles Pennington | Charles Pennington |
 Raymond SerraChief Sterns | Chief Sterns |
 Sam RockwellHead Thug | Head Thug |
| Kenn ScottTalkative Foot #2 | Talkative Foot #2 |
 Kevin EastmanCitizen (uncredited) | Citizen (uncredited) |
 Skeet UlrichThug (uncredited) | Thug (uncredited) |
 Scott WolfThug (uncredited) | Thug (uncredited) |
