 Tony GoldwynTarzan (voice) | Tarzan (voice) |
 Minnie DriverJane Porter (voice) | Jane Porter (voice) |
 Glenn CloseKala (voice) | Kala (voice) |
 Alex D. LinzYoung Tarzan (voice) | Young Tarzan (voice) |
 Rosie O'DonnellTerk (voice) | Terk (voice) |
 Brian BlessedClayton (voice) | Clayton (voice) |
 Nigel HawthorneProfessor Archimedes Q. Porter (voice) | Professor Archimedes Q. Porter (voice) |
 Lance HenriksenKerchak (voice) | Kerchak (voice) |
 Wayne KnightTantor (voice) | Tantor (voice) |
| TTaylor DempseyYoung Tantor (voice) | Young Tantor (voice) |
 Sherry LynnAdditional Voices (voice) | Additional Voices (voice) |
 Bob BergenAdditional Voices (voice) | Additional Voices (voice) |
 Rodger BumpassAdditional Voices (voice) | Additional Voices (voice) |
 Lily CollinsBaby Ape (voice) | Baby Ape (voice) |
 Jim CummingsAdditional Voices (voice) | Additional Voices (voice) |
 Debi DerryberryAdditional Voices (voice) | Additional Voices (voice) |
 Jason MarsdenAdditional Voices (voice) | Additional Voices (voice) |
 Chris SandersAdditional Voices (voice) | Additional Voices (voice) |
 Aria Noelle CurzonAdditional Voices (voice) | Additional Voices (voice) |
 Danny MannAdditional Voices (voice) | Additional Voices (voice) |
 Frank WelkerSabor (voice) (uncredited) | Sabor (voice) (uncredited) |
 Scott RecordAdditional Voices (voice) | Additional Voices (voice) |
| JJoseph AshtonAdditional Voices (voice) | Additional Voices (voice) |
| BBilly BodineAdditional Voices (voice) | Additional Voices (voice) |
| HHillary BrooksAdditional Voices (voice) | Additional Voices (voice) |
 Scott Martin GershinAnimals - Various (voice) | Animals - Various (voice) |
 Jack AngelMonkey (voice) | Monkey (voice) |
 Mickie McGowanTerk's Mother (voice) | Terk's Mother (voice) |
 Phil ProctorEnglish Captain / Scared Elephant (voice) | English Captain / Scared Elephant (voice) |
 Joe WhyteAdditional Voices (voice) | Additional Voices (voice) |
