When Bigshot Jones gives his unnamed dog to the All-For-One Club, Buckwheat quickly names the canine "Smallpox", inadvertently causing a city-wide panic.
| Actor | Role |
|---|---|
 Billie ThomasBuckwheat Thomas | Buckwheat Thomas |
 Billy LaughlinFroggy Laughlin | Froggy Laughlin |
 Janet BurstonJanet | Janet |
 Robert BlakeMickey Blake | Mickey Blake |
 Cordell HickmanBig Shot Jones | Big Shot Jones |
| DDickie HallNot listed | Not listed |
| FFrank WardNot listed | Not listed |
| MMargaret BertGossiper (voice) | Gossiper (voice) |
 Anita Sharp-BolsterGossiper | Gossiper |
 Willa Pearl CurtisBuckwheat's Mother | Buckwheat's Mother |
 Fern EmmettGossiper | Gossiper |
 Emmett VoganDr. Parkson | Dr. Parkson |
| DDorothy NewmannGossiper | Gossiper |