| EEben BrittonSelf - Former NFL Player (as Eben) | Self - Former NFL Player (as Eben) |
| DDr. Wendy BrownSelf - Political Theorist, UC Berkeley | Self - Political Theorist, UC Berkeley |
| AArianaSelf - College Sophomore | Self - College Sophomore |
| DDelaneySelf - College Junior | Self - College Junior |
| JJasper Holt-TezaSelf - College Senior (as Jasper) | Self - College Senior (as Jasper) |
| LLeighSelf - College Senior | Self - College Senior |
| AAnjan ChatterjeeSelf - Chair of Neurology, University of Pennsylvania | Self - Chair of Neurology, University of Pennsylvania |
| AAlan SchwarzSelf - Journalist, Author - ADHD Nation | Self - Journalist, Author - ADHD Nation |
| NNicholas RasmussenSelf - Author, On Speed | Self - Author, On Speed |
| NNathanaelSelf - Software Engineer | Self - Software Engineer |
| SSheila BrittSelf - Eben's Wife (as Brit) | Self - Eben's Wife (as Brit) |
| MMartha FarahSelf - Cognitive Neuroscientist, University of Pennsylvania | Self - Cognitive Neuroscientist, University of Pennsylvania |
| CCarl HartSelf - Chair of Psychology, Columbia University | Self - Chair of Psychology, Columbia University |
| LLawrence DillerSelf - Pediatrician, Author - Running on Ritalin | Self - Pediatrician, Author - Running on Ritalin |
| SSteve HinshawSelf - Psychologist, Author - The ADHD Explosion | Self - Psychologist, Author - The ADHD Explosion |
| BBlue WilliamsSelf - Artist Management (as Blue) | Self - Artist Management (as Blue) |
| BBiankaSelf - Leigh's Roommate | Self - Leigh's Roommate |
| LLiz JorgensenSelf - Psychotherapist | Self - Psychotherapist |
| PPeterSelf - Financial Analyst | Self - Financial Analyst |
| RRegina Holt-TezaSelf - Jasper's Mom (as Regina) | Self - Jasper's Mom (as Regina) |
| BBill HoltSelf - Jasper's Dad (as Bill) | Self - Jasper's Dad (as Bill) |
| MMaxineSelf - Blue's Mom | Self - Blue's Mom |
| KKeith ConnerSelf - Conducted First Controlled Ritalin Study | Self - Conducted First Controlled Ritalin Study |
| CCorey HebertSelf - Pediatrician | Self - Pediatrician |
| RRahiemSelf - High School Student | Self - High School Student |
| SSherrySelf - Rahiem's Mom | Self - Rahiem's Mom |
| JJesse LawlerSelf - Podcast Host, Smart Drug Smarts | Self - Podcast Host, Smart Drug Smarts |
| LLucas SiegelSelf - Co-Founder, AlternaScript (as Lucas) | Self - Co-Founder, AlternaScript (as Lucas) |
| MMatthew PiskorzSelf - Co-Founder, AlternaScript (as Matthew) | Self - Co-Founder, AlternaScript (as Matthew) |
| LLilySelf - Startup Publicist | Self - Startup Publicist |
