Tad accidentally unleashes an ancient spell, endangering the lives of his friends Mummy, Jeff, and Belzoni. With everyone against him and only helped by Sara, he sets off on an adventure to end the Curse of the Mummy.
| Actor | Role |
|---|---|
 Óscar BarberánTadeo Jones (voice) | Tadeo Jones (voice) |
 Luis PosadaMomia (voice) | Momia (voice) |
 Michelle JennerSara Lavrof (voice) | Sara Lavrof (voice) |
| AAnuska AlborgRamona (voz) | Ramona (voz) |
 Alexandra JiménezVictoria (voz) | Victoria (voz) |
| TTito ValverdePickle (voice) | Pickle (voice) |
 Cecilia SuárezAgent Ramirez (voice) | Agent Ramirez (voice) |
 José CorbachoRyu (voice) | Ryu (voice) |
 Berta CortésAnn (voice) | Ann (voice) |
| PPablo W.J. GómezBrian (voice) | Brian (voice) |
 Manuel BurqueMartin (voice) | Martin (voice) |
| RRoser AldabóEmilia (voice) | Emilia (voice) |
| GGloria GonzálezMrs. Wolfstrom (voice) | Mrs. Wolfstrom (voice) |
| MMarcelo NavarroReporter (voice) | Reporter (voice) |
 Ben CuraRayan (voice) | Rayan (voice) |
 Claudio SerranoGendarme (voice) | Gendarme (voice) |