 Tim DalySuperman / Clark Kent (voice) | Superman / Clark Kent (voice) |
 Dana DelanyLois Lane (voice) | Lois Lane (voice) |
 Clancy BrownLex Luthor (voice) | Lex Luthor (voice) |
 Malcolm McDowellJohn Corben (voice) | John Corben (voice) |
 Christopher McDonaldJor-El (voice) | Jor-El (voice) |
 Finola HughesLara (voice) | Lara (voice) |
 Mike FarrellJonathan Kent (voice) | Jonathan Kent (voice) |
 Shelley FabaresMartha Kent (voice) | Martha Kent (voice) |
 Tony JaySul-Van (voice) | Sul-Van (voice) |
 Corey BurtonBrainiac / Councilman / Cop (voice) | Brainiac / Councilman / Cop (voice) |
 George DzundzaPerry White (voice) | Perry White (voice) |
 David KaufmanJimmy Olsen (voice) | Jimmy Olsen (voice) |
 Lauren TomAngela Chen (voice) | Angela Chen (voice) |
 Tress MacNeilleMs. Stevenson / Annie's Mother / LexCorp Presenter (voice) | Ms. Stevenson / Annie's Mother / LexCorp Presenter (voice) |
 Jason MarsdenTeenage Clark Kent (voice) | Teenage Clark Kent (voice) |
| KKelly SchmidtLana Lang (voice) | Lana Lang (voice) |
 Miracle VincentDanitra Evans / Annie (voice) | Danitra Evans / Annie (voice) |
 Brad GarrettBibbo (voice) | Bibbo (voice) |
 Dorian HarewoodRon Troupe (voice) | Ron Troupe (voice) |
| NNick SavalasAttorney (voice) | Attorney (voice) |
 Charles HowertonWhirly Pilot / Hans - Terrorist Guard (voice) | Whirly Pilot / Hans - Terrorist Guard (voice) |
 Brian GeorgeCouncilman (voice) | Councilman (voice) |
 Roger RoseDriver Cop / Councilman (voice) | Driver Cop / Councilman (voice) |
 Vernee WatsonFemale Worker / Councilwoman (voice) | Female Worker / Councilwoman (voice) |
| JJesse BattenBaby Kal-El (voice) | Baby Kal-El (voice) |
