Ultraman Mebius is joined once again by Ultraman, Ultra Seven, Ultraman Jack, and Ultraman Ace, as well as three later Ultramen (Tiga, Dyna, and Gaia) to fight more powerful versions of familiar Ultra Monsters.
| Actor | Role |
|---|---|
 Hiroshi NaganoDaigo Madoka/Ultraman Tiga (Voice) | Daigo Madoka/Ultraman Tiga (Voice) |
 Takeshi TsurunoShin Asuka/Ultraman Dyna (Voice) | Shin Asuka/Ultraman Dyna (Voice) |
 Takeshi YoshiokaGamu Takayama/Ultraman Gaia (V2) (Voice) | Gamu Takayama/Ultraman Gaia (V2) (Voice) |
 Shunji IgarashiMirai Hibino/Ultraman Mebius (Voice) | Mirai Hibino/Ultraman Mebius (Voice) |
 Susumu KurobeShin Hayata/Ultraman (Voice) | Shin Hayata/Ultraman (Voice) |
 Jiro DanHideki Go/Ultraman Jack (Voice) | Hideki Go/Ultraman Jack (Voice) |
 Keiji TakamineSeiji Hokuto/Ultraman Ace (Voice) | Seiji Hokuto/Ultraman Ace (Voice) |
 Takami YoshimotoRena | Rena |
 Kurumi HashimotoHikari | Hikari |
 Kohji MoritsuguDan Moroboshi/Ultra Seven (Voice) | Dan Moroboshi/Ultra Seven (Voice) |
| MMomoka IizukaGirl Wearing Red Shoes | Girl Wearing Red Shoes |