Santo must investigate a secret conspiracy involving a spy training camp, a brainwashing plot, and a kidnapped Nazi scientist.
| Actor | Role |
|---|---|
 El SantoSanto | Santo |
 Lorena VelázquezAna Silva | Ana Silva |
 Elsa CárdenasSeñorita Thomas | Señorita Thomas |
 Dagoberto RodríguezSebastián | Sebastián |
 César del CampoTopacio | Topacio |
| GGuillermo GalvezOtto | Otto |
| RRoxana BelliniElke | Elke |
| PPatricia FerrerDebbie | Debbie |
 Fernando OsésEsbirro de Sebastián | Esbirro de Sebastián |
| ÁÁngela RodríguezPelirroja, asistente de Elke | Pelirroja, asistente de Elke |
| CCarlos SuárezEsbirro de Sebastián | Esbirro de Sebastián |
| CCarlos LeónMesero / agente interpol | Mesero / agente interpol |
| CCarlos HenningsDr. Thomas | Dr. Thomas |
| YYolanda PonceNot listed | Not listed |
 Juan GallardoDr. Muller | Dr. Muller |