Following the events of 'Stree', the town of Chanderi is being haunted again. This time, women are mysteriously abducted by a terrifying headless entity. Once again, it's up to Vicky and friends to save their town and loved ones.
| Actor | Role |
|---|---|
 Rajkummar RaoVicky | Vicky |
 Shraddha KapoorUnnamed Woman | Unnamed Woman |
 Aparshakti KhuranaBittu | Bittu |
 Abhishek Banerjee'Jana' Janardan | 'Jana' Janardan |
 Pankaj TripathiRudra | Rudra |
 Anya SinghChitti | Chitti |
 Tamannaah BhatiaShama | Shama |
| SSunil KumarSarkata / Udaybhan | Sarkata / Udaybhan |
| BBhumi RajgorStree | Stree |
 Varun DhawanBhaskar | Bhaskar |
 Akshay KumarUdaybhan's Descendent | Udaybhan's Descendent |
 Atul SrivastavaVicky's Father | Vicky's Father |
 Sunita RajwarJana's Mother | Jana's Mother |
 Mushtaq KhanSarpanch | Sarpanch |
| AArvind BilgaiyanJana's Father | Jana's Father |
 Badri ChavanBadri | Badri |
 Aakash DabhadeNarendra | Narendra |
 Simran SharmaMamata | Mamata |
| AAjay PalPostman | Postman |
| MMehrunnisa Mustaqeem KhanDurga | Durga |
| BBadri Prasad ChavanLokesh | Lokesh |
| VVipasha ArvindAnju Bhabhi | Anju Bhabhi |
 Amar KaushikHomeless Stud | Homeless Stud |