After Nina Leeds finds out that insanity runs in her husband's family, she has a love child with a handsome doctor and lets her husband believes the child is his.
| Actor | Role |
|---|---|
 Norma ShearerNina Leeds | Nina Leeds |
 Clark GableDr. Ned Darrell | Dr. Ned Darrell |
 Alexander KirklandSam Evans | Sam Evans |
 Ralph MorganCharlie Marsden | Charlie Marsden |
 Robert YoungGordon Evans as a young man | Gordon Evans as a young man |
 May RobsonMrs. Evans | Mrs. Evans |
 Maureen O'SullivanMadeline Arnold | Madeline Arnold |
 Henry B. WalthallProfessor Leeds | Professor Leeds |
 Mary AldenMary, Leeds' Maid | Mary, Leeds' Maid |
 Tad AlexanderGordon Evans as a child | Gordon Evans as a child |