The Stoner Snakes are back as they try to think of an idea for a sequel while a big bad snake wants to take over the world and remove the friendly stoners snakes so snakes can rule the world as REAL snakes and not stoners.
| Actor | Role |
|---|---|
 Matthew Mark HunterCamper / Old Man / Boy Scout / Benjamin (voice) | Camper / Old Man / Boy Scout / Benjamin (voice) |
| SShawn NessLenny / Santiago (voice) | Lenny / Santiago (voice) |
| SSteve StroutMilo (voice) | Milo (voice) |
| MMatt SkinnerGoliath (voice) | Goliath (voice) |
| JJason PoljakSmoke Shop Manager Jason | Smoke Shop Manager Jason |
| TTim GrossStoner Snake Fan | Stoner Snake Fan |
| TTom GrossStoner Snake Fan | Stoner Snake Fan |
 Madeline DeeringStoner Snake Fan | Stoner Snake Fan |
 Chris RhydingsStoner Snake Fan | Stoner Snake Fan |
 Kelsey LivengoodConvention Guest | Convention Guest |
| AAddison BinekConvention Guest | Convention Guest |
 Rudy LedbetterMilo Sleeping Victim | Milo Sleeping Victim |
 Lloyd KaufmanSammy Snake (Voice) | Sammy Snake (Voice) |
| BBozo HunterClown Mascot | Clown Mascot |
| CChris LacksTrash man | Trash man |