Three gangsters vie for control of the streets of Philadelphia.
| Actor | Role |
|---|---|
 Beanie SigelBeans | Beans |
 Damon DashDame | Dame |
 Omillio SparksBaby Boy | Baby Boy |
 N.O.R.E.El Pollo Loco | El Pollo Loco |
| FFreewayFree | Free |
 Roselyn SánchezSexy Lawyer | Sexy Lawyer |
| MMichael BenttBiggis (El Plaga) | Biggis (El Plaga) |
 Sundy CarterAisha | Aisha |
 Chance KellyGuard | Guard |
 Ol' Dirty BastardDirt McGirt | Dirt McGirt |
 YeSelf | Self |
 Mariah CareyProfessionally Dressed Woman | Professionally Dressed Woman |
 Cam'ronCam'ron | Cam'ron |
 Jim JonesJimmy Jones | Jimmy Jones |
 Juelz SantanaJuelz Sanchez | Juelz Sanchez |
| LLeonette ScottNot listed | Not listed |
| LLil' FameFame | Fame |
| YYoung NeefNeef | Neef |
| YYoung ChrisChris | Chris |
| DDuan GrantP-Nut | P-Nut |
| BBilly DanzeBilly Danze | Billy Danze |
| FFox MOPFox | Fox |
| DDenimSelf | Self |
| NNicole WraySelf | Self |
 Angie MartinezMissy (Tuesday Night) | Missy (Tuesday Night) |
 Bernard HopkinsO.G. | O.G. |
| LLoonLoco's Father | Loco's Father |
 Omahyra MotaLoco's Mother | Loco's Mother |
 Derron 'Smokey' EdingtonInmate | Inmate |
 Rob StapletonInmate | Inmate |