 Joel McCreaJosiah Doziah Gray | Josiah Doziah Gray |
 Ellen DrewHarriet Gray | Harriet Gray |
 Dean StockwellJohn Kenyon | John Kenyon |
 Alan HaleJed Isbell | Jed Isbell |
 Lewis StoneDr. Daniel Kalbert Harris, Sr. | Dr. Daniel Kalbert Harris, Sr. |
 James MitchellDr. Daniel Kalbert Harris, Jr. | Dr. Daniel Kalbert Harris, Jr. |
 Amanda BlakeFaith Radmore Samuels | Faith Radmore Samuels |
 Juano HernándezUncle Famous Prill | Uncle Famous Prill |
 Charles KemperProf. Sam Houston Jones | Prof. Sam Houston Jones |
 Connie GilchristSarah Isbell | Sarah Isbell |
 Ed BegleyLon Backett | Lon Backett |
 Jack LambertPerry Lokey | Perry Lokey |
 Arthur HunnicuttChloroform Wiggins | Chloroform Wiggins |
 Marshall ThompsonNarrator (adult John Kenyon) (voice) | Narrator (adult John Kenyon) (voice) |
 James ArnessRolfe Isbell (uncredited) | Rolfe Isbell (uncredited) |
| PPolly BaileyMrs. Belsher (uncredited) | Mrs. Belsher (uncredited) |
 Chuck CourtneyJed Isbell (uncredited) | Jed Isbell (uncredited) |
 Adeline De Walt ReynoldsGranny Gailbraith (uncredited) | Granny Gailbraith (uncredited) |
 Edmund GloverClyde Chapman (uncredited) | Clyde Chapman (uncredited) |
| JJessica GraysonBessie - Maid (uncredited) | Bessie - Maid (uncredited) |
 Victor KilianNed (uncredited) | Ned (uncredited) |
| PPatricia MillerMrs. Chapman (uncredited) | Mrs. Chapman (uncredited) |
 Rhea MitchellMrs. Backett (uncredited) | Mrs. Backett (uncredited) |
| NNorman OllestadChase Isbell (uncredited) | Chase Isbell (uncredited) |
 Harry 'Snub' PollardBartender (uncredited) | Bartender (uncredited) |
| BBen WatsonGene Caldwell (uncredited) | Gene Caldwell (uncredited) |
| WWilson WoodThad Carroll (uncredited) | Thad Carroll (uncredited) |
 Eula GuyTownswoman (uncredited) | Townswoman (uncredited) |
 Frank MillsDrunk in Saloon (uncredited) | Drunk in Saloon (uncredited) |
 Jessie ArnoldAnnie (voice) (uncredited) | Annie (voice) (uncredited) |
