In the second "Ironside" movie, the Chief has his spine jolted during a hospital encounter with a narcotics pusher, not only raising the possibility for an operation that might cure his paralysis but also putting him in jeopardy because he can identify the man who had just shot a guard.
| Actor | Role |
|---|---|
 Raymond BurrRobert Ironside | Robert Ironside |
 Barbara AndersonEve Whitfield | Eve Whitfield |
 Joseph CottenDr. Ben Stern | Dr. Ben Stern |
 Troy DonahueFather Dugan | Father Dugan |
 Don GallowayDet. Sgt. Ed Brown | Det. Sgt. Ed Brown |
 Don MitchellMark Sanger | Mark Sanger |
 Margaret O'BrienLouise Prescott | Louise Prescott |
 Andrew PrineErnie Clark | Ernie Clark |
 Mel ScottRalph Fellows | Ralph Fellows |
 Lilia SkalaSister Agatha | Sister Agatha |
 Don StroudAlbee | Albee |