 Isabela MercedLucky Prescott (voice) | Lucky Prescott (voice) |
 Julianne MooreAunt Cora (voice) | Aunt Cora (voice) |
 Marsai MartinPrudence Granger (voice) | Prudence Granger (voice) |
 Mckenna GraceAbigail Stone (voice) | Abigail Stone (voice) |
 Walton GogginsHendricks (voice) | Hendricks (voice) |
 Jake GyllenhaalJim Prescott (voice) | Jim Prescott (voice) |
 Gary A. HeckerHorse Vocals (voice) | Horse Vocals (voice) |
 Eiza GonzálezMilagro Navarro Prescott (voice) | Milagro Navarro Prescott (voice) |
 Andre BraugherAl Granger (voice) | Al Granger (voice) |
 Lucian PerezSnips Stone (voice) | Snips Stone (voice) |
 Joe HartJames Prescott Sr. (voice) | James Prescott Sr. (voice) |
| AAlejandra BlengioValentina (voice) | Valentina (voice) |
 Bridget HoffmanBaby Lucky Prescott (voice) | Baby Lucky Prescott (voice) |
 Jerry ClarkeWrangler / Llama Cowboy (voice) | Wrangler / Llama Cowboy (voice) |
 Gino MontesinosWrangler / Rodeo Cowboy (voice) | Wrangler / Rodeo Cowboy (voice) |
 Gary Anthony WilliamsWrangler (voice) | Wrangler (voice) |
 Renie RivasLady with Dog (voice) | Lady with Dog (voice) |
 Lew TempleConductor (voice) | Conductor (voice) |
 Eric TiedeTownsfolk | Townsfolk |
