Drama illuminating Dr James Niven's efforts to protect the people of Manchester from the 1918 Spanish influenza pandemic as millions of soldiers returned home from the Great War.
| Actor | Role |
|---|---|
 Mark GatissErnest Dunks | Ernest Dunks |
 Charlotte RileyPeggy Lytton | Peggy Lytton |
 Bill PatersonDr James Niven | Dr James Niven |
 Raffey CassidyEllen | Ellen |
 Paul FreemanSir Arthur Newsholme | Sir Arthur Newsholme |
 Kenneth CranhamMJ O'Loughlin | MJ O'Loughlin |
 Ian MercerStanford | Stanford |