Two former backup soul singers, Louis and Floyd, have not spoken to each other in 20 years, and reluctantly agree to travel across the country together to a reunion concert to honor their recently-deceased lead singer. Cleo, a beautiful young woman who is believed to be Floyd's daughter, accompanies them as a new singer.
| Actor | Role |
|---|---|
 Samuel L. JacksonLouis Hinds | Louis Hinds |
 Bernie MacFloyd Henderson | Floyd Henderson |
 Sharon LealCleo | Cleo |
 Adam HerschmanPhillip | Phillip |
 Sean HayesDanny Epstein | Danny Epstein |
 Affion CrockettLester | Lester |
 Jackie LongZig-Zag | Zig-Zag |
 Mike EppsDuane Henderson | Duane Henderson |
 John LegendMarcus Hooks | Marcus Hooks |
 Isaac HayesSelf | Self |
 Vanessa del RioFull-Figured Neighbor | Full-Figured Neighbor |
 Ken DavitianArdesh Kezian | Ardesh Kezian |
 Jennifer CoolidgeRosalee | Rosalee |
 Jackie JohnsonWeather Woman | Weather Woman |
 P.J. ByrneFloyd's Doctor | Floyd's Doctor |
 Michael FranklinTrumpet Player | Trumpet Player |
 Sara EriksonChastity | Chastity |
 Terrell J. RamseyPay-Pay | Pay-Pay |
 Maurice DuBoisNewscaster | Newscaster |