A Southern Italian family is suddenly faced with AIDS. One of them has it. Which friend or family member could have begun this cycle of infection? The characters include a vain housewife, her straight-laced husband, her gay brother, and her husband's and brother's best friend. Hilarious mayhem ensues.
| Actor | Role |
|---|---|
 Giovanni EspositoMario Cirillo | Mario Cirillo |
| CCristina LiberatiRosaria Cirillo | Rosaria Cirillo |
 Paolo SassanelliDino | Dino |
 Manrico GammarotaSabino Lamonaca | Sabino Lamonaca |
 Nino FrassicaBanchiere | Banchiere |
 Vladimir LuxuriaSé stessa | Sé stessa |
 Joe D'AmatoRegista hardcore | Regista hardcore |
 Vincenzo AronicaScienziato | Scienziato |
| MMario De MartinoEstetista | Estetista |
 Stefania Orsola GarelloProprietaria della pensione | Proprietaria della pensione |
| SSerafino IorliPranoterapeuta | Pranoterapeuta |